theoretically, how might researchers disrupt signal transduction pathways as possible treatments for cancer?

Answers

Answer 1

Theoretically, by interfering with the activity of protein kinases involved in cell cycle regulation, researchers may alter signal transduction pathways as potential cancer treatments.

Major roles in the development of tumors are played by protein kinases, which are important in cell cycles. These protein kinases undergo mutations in large numbers. Tumor growth would continue since cell cycles couldn’t be stopped.

G protein-coupled receptors are common. Therefore, changing and inactivating G protein receptors will be very beneficial. The majority of these kinases undergo phosphorylation and dephosphorylation processes. In cells containing cancer, targeting these would interfere with signal transmission.

Therefore, the right response is option D.

The complete question is:-

Theoretically, how might researchers disrupt signal transduction pathways as possible treatments for cancer?

Stimulate the production of cAMP in cancer cells.

b. inactivate epinephrine receptors on cancer cells.

c. alter G protein-coupled receptors involved in cell cycle regulation to be active in the absence of their normal signaling molecules.

D. disrupt the function of protein kinases involved in cell cycle regulation.

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Related Questions

the trait of bipedalism is a shared, derived trait of which group? the trait of bipedalism is a shared, derived trait of which group? family hominidae primates subfamily homininae australopithecus tribe hominini eutherian mammals bonobos rodents and primates the genus homo

Answers

The trait of bipedalism is a shared and derived trait of Bipedal African great apes, who belong to family Hominidae, subfamily Australopithecus.  

Bipedal African great apes belong to the tribe Hominini. Present day Homo sapiens are fully bipedal, with large brain capacity, larger body mass, less prominent jaw, and characterize the features which allows the manipulation of objects, long-distance terrestrial movement, use of teeth for chewing/ biting/ cutting a nutrient rich diet. Bipedal refers to the locomotion which is reflected by walking upright, using only two legs without any other support. This ability to walk straight upright is the defining attribute of the hominin lineage. This feature of early man was first observed in the fossils collected from African continent and they must have been probably the Australopithecus.

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if cytosine makes up 42% of the nucleotides in a sample of dna from an organism. what percentage of nucleotides will be thymine?

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Thymine will make up 8%. DNA is double stranded, and the same pairings of nucleotides always occur:

Cytosine and guanine couple (G-C)

Adenine and thymine are paired (A-T)

In this instance, cytosine accounts for 42%, which implies that guanine accounts for 42% as well. So, a G-C base pair makes up 84% of the DNA.One of the four nucleotide bases of DNA, along with adenine (A), cytosine (C), and guanine, is thymine (T) (G).

This leaves 16% for the A-T base pair: 8% adenine and 8% thymine. Thymine nucleotides on one strand pair with adenine bases on the other strand in a double-stranded DNA molecule. Information in DNA is encoded by the four nucleotide bases' order.

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If a cell increases the activity of its actin severing proteins, will it lead in the short term to more or less actin polymer mass?

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Answer: If the concentration of free actin monomers is above the Cc for both the plus and minus ends, then MORE polymer will result. If the concentration of free actin monomers is below the Cc for both the plus and minus ends, then LESS polymer will result.

Explanation:

which portion of the adrenal gland secretes epinephrine, norepinephrine, and a trace of dopamine? multiple choice question. adrenal cortex

Answers

Epinephrine, norepinephrine, and a very small amount of dopamine are secreted by the adrenal medulla component of the adrenal gland.

The triangle-shaped glands on top of the kidneys are known as the adrenal glands or suprarenal glands. Hormones produced by your adrenal glands regulate a number of vital bodily functions, including your immune system, blood pressure, stress response, metabolism, and others. The brain has some control over the adrenal glands.

The adrenomedullary gland consists of the medulla and cortex. The medulla generates catecholamines such as epinephrine and norepinephrine, whereas the cortex produces steroid hormones such as glucocorticoids, mineralocorticoids, and adrenal androgens.

The adrenal medulla produces the chemicals adrenaline (also known as epinephrine) and noradrenaline (also known as norepinephrine). These control blood pressure and heart rate and are essential in the stress response. They serve as neurotransmitters as well.

According to need, the body regulates corticosteroid levels. Early in the day tends to have substantially higher levels than later in the day. The levels of corticosteroids rapidly rise when the body is under stress due to disease or another factor.

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How long ago was the primary evidence of photosynthesis?

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3 BC is when photosynthesis started

name 3 shared targets of the sympathetic and parasympathetic system. what are the effects each system has on the target?

Answers

The sympathetic and parasympathetic neural systems, which both regulate the same bodily regions and general bodily activities but have opposing effects, are found in the autonomic nervous system.

The modulation of numerous essential processes, including as respiration and heart contraction, depends on the sympathetic and parasympathetic neural systems. For instance, the parasympathetic and sympathetic nervous systems work together to maintain healthy blood pressure, vagal tone, and heart rate. The lungs, heart, smooth muscle, and exocrine and endocrine glands, including the sweat and salivary glands, are among the major organs impacted. Together, the two systems maintain your body balanced. Blood pressure increases, the fight-or-flight response, pupil dilation, and stimulation of the adrenal medulla are all caused by the sympathetic nervous system.

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Work out the potential difference if 11,500j of energy are transferred by 50c of charge.

Answers

The potential difference if 11,500j of energy are transferred by 50c of charge IS 450V.

The following data were obtained from the question:

Energy (E) = 11500J

Charge (Q) = 50C

Potential difference (V) =.?

The energy, E stored in a capacitor is related to the charge, Q and potential difference, V by the following equation

E = ½QV

With the above equation, we can easily calculate the potential difference as follow:

E = ½QV

11500 = ½ × 50 × V

11500 = 25 × V

Divide both side by 25

V = 11500/25

V = 460V.

Therefore, the potential difference is 460V when 11,500j of energy are transferred by 50c of charge.

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During splicing, which molecular component of the spliceosome catalyzes the excision reaction?

Answers

The correct option is C) RNA ,The term "RNA" stands for ribonucleic acid, a complex substance with a large molecular weight that is used in the creation of proteins in cells.

In some viruses, takes the role of DNA (deoxyribonucleic acid) as a carrier of genetic information.

Spliceosome is a complex machinery that performs splicing (removal of the introns from the primary mRNA transcript) and alternative splicing (re-combination of different exons which increases genetic diversity).

Spliceosome is composed of small nuclear RNAs (five of them) and proteins that together make snRNPs-small nuclear ribonucleo proteins.

Spliceosome is a ribozyme, meaning that RNAs inside are capable of catalyzing reactions. Catalyzed reactions by spliceosome are the removal of introns, and the ligation of the exons.

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Full Question ;

During splicing, which molecular component of the spliceosome catalyzes the excision reaction?

A) protein B) DNA C) RNAD) lipid E) sugar

In most eukaryotes, only about 1.5% of the genome codes for proteins. what types of sequences make up the rest of the genome?

Answers

Eukaryotes and prokaryotes produce ATP as their primary metabolic energy source during cellular respiration.

Eukaryote is a cell or organism with a well-defined nucleus. Eukaryotic cells have a nuclear membrane surrounding the nucleus, which contains well-defined chromosomes bodies containing genetic material.

The main difference between prokaryotes and eukaryotes is the membrane-bound nucleus. Most notably, eukaryotes have membrane-bound nuclei, whereas prokaryotes do not.

Eukaryotic cells. Eukaryotic cells are defined as cells containing an organized nucleus and organelles enclosed in membrane-bound organelles. Examples of eukaryotic cells are plants, animals, protists, and fungi. Your genome is organized into chromosomes.

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What is the name given to the process in which a DNA strand is used as a template for making mRNA?

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Transcription is the procedure via way of means of which the facts in a strand of DNA is copied into a brand new molecule of messenger RNA (mRNA).

DNA competently and stably shops genetic cloth withinside the nuclei of cells as a reference, or template. Each time a mobileular divides, every of its double strands of DNA splits into unmarried strands. Each of those unmarried strands acts as a template for a brand new strand of complementary DNA. As a result, every new mobileular has its very own whole genome.

This procedure is referred to as DNA replication.During transcription, the DNA of a gene serves as a template for complementary base-pairing, and an enzyme referred to as RNA polymerase II catalyzes the formation of a pre-mRNA molecule, that's then processed to shape mature mRNA.

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are any organisms harmed during symbiotic relationships 

Answers

Answer:

No

Explanation:

organisms are not typically harmed during symbiotic relationships. Symbiotic relationships are mutually beneficial for both organisms involved, and they can range from commensalism, where one organism benefits and the other is unaffected, to mutualism, where both organisms benefit.

many organisms must consume others to survive. which scenarios represent consumptive species interactions?

Answers

The consumptive species interactions are:

1. A lion hunting a wildebeest in the savanna

2. A shark consuming a school of fish

3. A tree absorbing water and minerals from the soil

4. A bee collecting nectar from a flower

Organisms are living entities, such as plants, animals, fungi, and bacteria, that are composed of cells and have the ability to grow, reproduce, and adapt to their environment. They are the basis of all life on Earth.

1. A lion hunting and eating a wildebeest: This is an example of predation, where the lion is the predator and the wildebeest is the prey. The lion consumes the wildebeest in order to obtain energy and nutrients.

2. A heron eating a fish from a river: This is an example of predation, where the heron is the predator and the fish is the prey. The heron consumes the fish in order to obtain energy and nutrients.

3. A bee collecting nectar from a flower: This is an example of mutualism, where the bee and flower both benefit from the interaction. The bee collects nectar from the flower in order to obtain energy, while the flower is pollinated and reproduces.

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what is the expected functional consequence of movement of a transposable element within the genome?

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The expected functional consequences of the movement of transposable elements in the genome:

Increases protein production.Decreased protein production.Abnormal gene transcription.

Transposable is the event of moving the DNA sequence in the genome from one position to another. Elements that undergo displacement are called transposons. Humans have transverse elements that vary up to 44% of all human DNA. There are four basic types of transposable elements, namely LINEs (long interspersed nuclear elements), SINE's (short interspersed nuclear elements), retrovirus-like elements, and cut-and-paste transposons.

A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position in the genome, sometimes creating or reversing mutations and changing the cell's genetic identity and genome size. Transposition often results in the duplication of the same genetic material.

Thus, transposable will cause increased protein production, decreased protein production, and abnormal gene transcription.

This question should be equipped with options

a) All of the listed responses are correctb) Increased production of a proteinc) Decreased production of a proteind) Abnormal transcription of a genee) None of the listed responses are correct

The true choice is A

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Apply If South America were not there
explain how the direction of the South
Equatorial current would be different.

Answers

The direction of South America were not there.

What is direction?

Direction is defined as the  path os something takes, the path that is must be taken by  to the reach of  a specific place, the way in this  which something by  starting to develop or to the  way you are facing the problem. An example of direction is when you are going right instead of left.

The direction of the Southern Equatorial currently changes. The main reason is the continental  deflection. If South America is not there,we have to explain how the direction of to the South Equatorial is  currently would not be different. If the continental was not there, then this is the direction would not be  change. The current would continue moving to the West.

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light passes through the entire thickness of the neural layer of the retina to excite the photoreceptors.
A) True
B) False

Answers

Answer:

A. True

light passes through the entire thickness of the neural layer of the retina to excite the photoreceptors.

Option A.true good luck

under which circumstances are amino acids not metabolized via oxidative degradation? a. starvation b. plants growing in nutrient-rich soils c. normal protein turnover d. uncontrolled diabetes

Answers

Animals experience an oxidative breakdown of amino acids under three different metabolic conditions: 1. Some amino acids released from protein breakdown that are not required for new protein synthesis go through oxidative degradation during the normal production and destruction of cellular proteins (protein turnover).

Without going through oxidation, some amino acids can be deaminated to release NH3. (a) Amino acid dehydrases: Serine, threonine, and homoserine are the hydroxy amino acids. They go via non-oxidative deamination, which PLP-dependent dehydrases catalyze (dehydratases).In oxidative deamination, amino groups are taken off of amino acids, producing matching keto acids and ammonia in the process. As a result, amino acids are in a sense "wasted" when they are not employed to create protein or other nitrogen-containing molecules.

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what is the difference between the allosteric and torpedo models of eukaryotic transcriptional termination?

Answers

The difference between the allosteric and torpedo models of eukaryotic transcriptional termination  is destabilization after transcription

The allosteric model is that RNA pol II becomes destabilized after transcription of the poly A signal . sequence while the torpedo model is that the polymerase is physically removed from the DNA.

The allosteric model suggests that termination occurs due to the structural change of the RNA polymerase unit after binding to or losing some of its associated proteins, making it detach from the DNA strand after the signal.Transcription termination occurs in a reaction coupled to RNA 3′-end processing. Most eukaryotic mRNA precursors are cleaved in a site-specific manner in the 3′-untranslated region, followed by polyadenylation of the upstream cleavage product. A large number of proteins is involved in these reactions.The concerted model of allostery, also referred to as the symmetry model or MWC model, postulates that enzyme subunits are connected in such a way that a conformational change in one subunit is necessarily conferred to all other subunits. Thus, all subunits must exist in the same conformation.

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what is the most essential natural resource necessary to produce america's biggest crop? (the resource without which the crop will fail). a. pesticides b. oil c. water d. muscle energy (human

Answers

All farming systems are based on land and water resources, and maintaining these resources is essential to sustaining and enhancing food production. Drought, flooding, pest infestation, or any other tragedy might cause crops to fail. Crop failure is not caused by infertility of the ground. Lower yields are the result.

Perrin pointed out that these fundamental resources include land, water, and other natural resources as well as important aspects like climate and ecological resilience. One of the most valuable natural resources that emerge from trees is water.Natural land regions benefit from the nutrients, water, oxygen, and heat provided by soil. The third essential resource for people, animals, plants, and all other living things in a natural setting is air.

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an ecologist is studying the interaction between the wolves in yellowstone national park and the deer and rabbits that they hunt. the ecologist also noticed that in the areas where the wolves hunt, there are more small predators such as weasel and coyote. what type of ecologist is this?

Answers

Community ecologist  type of ecologist is this . An ecological community is defined as a group of species that are commonly found together.

The term "ecological community" refers to a collection of species that are frequently found together. Ecological communities can be assemblages of animals or plants that have similar habitat needs and may interact with one another or depend on comparable environmental processes.

An ever-expanding and comprehensive area of ecology is community ecology. Ecologists look at the variables that affect species distribution, community structure, and biodiversity. Interactions with the abiotic environment and the wide variety of interactions that take place between species are two examples of these elements.

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which structure or component of the small intestine is important to antimicrobial defense?

Answers

The epithelial surface of the intestine plays a critical role in the protection of antimicrobial defense.

Which intestinal cells produce antibacterial?

Paneth cells are the main producers of antimicrobial peptides in the intestinal tract. These cells secrete considerable quantities of α-defensin peptides, the amplest antimicrobial peptides in the human intestine.

there are no Paneth cells, which is a specialized intestinal epithelial cell type that produces antimicrobial.

So we can conclude that Small intestinal mucosa is lined by a simple circular epithelium which consists primarily of permeable cells (enterocytes), with separate goblet cells and occasional enteroendocrine cells.

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What type of reaction is hydrocarbon burning?

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Type of reaction in hydrocarbon burning is called exothermic. Fuel and oxygen undergo an exothermic reaction that results in the gaseous material (smoke) as the end result. Compounds consisting solely of hydrogen and carbon are known as hydrocarbons.

Incomplete combustion and full combustion are the two forms of combustion. A hydrocarbon and oxygen undergo a chemical reaction known as hydrocarbon combustion, which results in the production of carbon dioxide, water, and heat. Organic substances known as hydrocarbons include both carbon and hydrogen. They are well known for being the main ingredient in fossil fuels including coal, natural gas, and oil.

If complete ignition happens, a hydrocarbon burns with a blue flame. Hydrocarbons begin to burn as their molecular weight rises, with a yellow flame indicating incomplete burning. With rising molecular weights, combustion of hydrocarbons becomes more challenging. An exothermic reaction constantly releases energy, frequently in the form of heat. Exothermic reactions are the universal type of combustion. A substance burns as it reacts with oxygen to release energy in the form of heat and light during combustion.

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25. explain how two critical factors influence whether a species will evolve toward semelparity or iteroparity.

Answers

The possibility that the adult will live and reproduce again, as well as the likelihood that the young will survive and reproduce, are two important elements that determine whether a species will evolve toward semelparity or iteroparity.

One semelparity reproduces before dying. Iteroparity results in recurrent offspring. Semelparity is preferred and the survival rate of offspring is poor in changing or uncertain circumstances. Disease, competition, and predation are examples of variables that depend on density. Semelparity  species size can be correlated positively or negatively with density-dependent characteristics. These growth-restricting iteroparity elements have a positive association with population size, increasing as the species grows.

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which of the following is the main factor for extinction rates? group of answer choices distance to the mainland island age the water between the islands (e.g., currents, temerature, depth) island size

Answers

Distance to the mainland island is the main factor for extinction rates according to the Island biogeography theory.

According to island biogeography theory, the size of the island and its distance from the mainland are the two variables that have the biggest impact on the species richness in natural ecosystems on an island. These elements have an impact on extinction and immigration rates simultaneously. The hypothesis states that islands that are closer to the continent have a better likelihood of absorbing immigrants than islands that are farther away. This is how distance has an impact. The relationship between island size and species diversity reflects the impact of size. Compared to larger islands, the likelihood of extinction is higher on smaller islands. More species may exist on larger islands than on smaller ones. When two islands of the same size and are separated from the mainland by different distances, they will both have the same rate of extinction, but the island closest to the continent will have a higher rate of immigration and, consequently, a greater variety of species. On the island that is nearer to the continent, the S value will be higher.

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30 pts Please help me

What is the end result of the cell cycle, compared to the original cell?

Explain.

Answers

The cell cycle is a cycle of stages that cells pass through to allow them to divide and produce new cells.

What is cell cycle?

Cell cycle is defined as a series of events that take place in a cell, resulting in the duplication of DNA and division of cytoplasm and organelles to produce two daughter cells.

cell cycle was discovered by Prevost and Dumas (1824) while studying the cleavage of zygote of Frog. It is a series of stages a cell passes through, to divide and produce new cells.

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which mammals were found to have a vocal range of 7 octaves, nearly twice that of humans?

Answers

Bats  were found to have a vocal range of 7 octaves, nearly twice that of humans.

What is vocal range?

Vocal range, in its broadest sense, refers to the entire range of notes that a singer's voice is capable of producing, from the lowest note to the highest note. Range, then, is the difference between the highest and lowest notes a singer is capable of singing.

Three and a third octaves are typical for human vocal range.

Being put into one of these categories merely indicates where your voice is most naturally strong; it does not preclude you from singing other notes. These vocal range categories are bass, baritone, tenor, alto, mezzo-soprano, and soprano, in that order.

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a researcher placed a culture of cyanobacteria under green lights. within a few weeks, the appearance of the cyanobacteria changed from green to red. the researcher claimed the color change in the culture was the result of an adaptation allowing greater photosynthesis.

Answers

The best argument in favor of this assertion is that green light causes an increase in the production of phycoerythrin pigment molecules, which allows more green light to be absorbed and speeds up photosynthesis.

What is the rate of photosynthesis?

The effectiveness of the pigments that absorb sunlight during this process determines how much oxygen and simple carbohydrates (glucose molecules) are created by a unit of time, which is referred to as the photosynthesis rate.

The number of photons absorbed from solar radiation, which depends on the amount of sunlight and the classes or types of pigments present in the photosynthetic cells—either plan cell or possibly algal cells—is what causes the photosynthesis rate in a given environmental state to be very variable.

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place the following into the correct order to represent the effects of angiotensin ii on tubular reabsorption.

Answers

In the attached file, the effects of angiotensin II on tubular reabsorption are depicted in the proper sequence.

What is the process of tubular reabsorption?

The procedure that removes solutes and water from the filtrate and returns them to your circulation is known as tubular reabsorption. Reabsorption refers to the fact that this is their second absorption, the first being when they entered the circulation from the digestive tract following a meal.

The location of tubular reabsorption?

The second crucial stage in the production of urine is tubular reabsorption. Amino acids, glucose, and salts are only a few of the solutes that are mostly reabsorb able in the proximal portion of the tubule.

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When basilar membrane moves, ______ of spiral organ hair cells distort because they are anchored by tectorial membrane, distortion initiates nerves signals.

Answers

When basilar membrane moves, The stereocilia of spiral organ hair cells distort because they are anchored by tectorial membrane, distortion initiates nerves signals.

What is basilar membrane?

The basilar membrane is the major  mechanical element  that reside in the inner ear. Which can be seen as a stiff structural element within the cochlea of the inner ear that  separates two liquid-filled tubes that run along the coil of the cochlea in the ear.

What are hair cell?

Hair cells which is also known as Cochlear hair cells are the primary sensory receptors of both the auditory system and the vestibular system in the  inner ears of most if not all vertebrates. They can be found near the center of the basilar membrane where vibrations will be at it high point.

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What happens during Mr. Whymper's visit to Animal Farm?

Answers

Every Monday, Mr. Whymper starts making a visit to the farm, and Napoleon gives him orders for various goods. The pigs start residing in the farmhouse, allegedly breaking one of the Ten Commandments by sleeping on beds.

Mr. Whymper, a Willingdon-based lawyer, had volunteered to serve as Animal Farm's point of contact with the outside world and would come to the farm each Monday morning to pick up instructions.

The animals are trained to loudly lie about ration increases whenever Mr. Whymper pays a visit, and the empty food barrels are made to look full. Whymper serves as "a middleman between the outer world and Animal Farm."

He continuously makes an appearance in the supporting role to relay signals from Napoleon to the other humans. He is the first human the pigs allow contact with after the Rebellion.

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helpppp giving brainly ​

Answers

The chromosomes in the vegetative, reproductive, and or the zygote or embryo cells of the illustrated animals would be as below.

Diploid and haploid cells

Diploid cells are mostly vegetative cells with double chromosome sets (2n). Haploid cells, on the other hand, are gametes or reproductive cells with just a set of chromosomes (n).

During fertilization, male and female gametes fuse together to form diploid zygotes or embryo cells (2n).

Thus:

A corn with 10 chromosome pair will have: 10 x 2 = 20 chromosomesThe number of chromosomes in the pollen and ovum of the corn would be 10 chromosomes each.The seeds, being a product of fertilization will have 2n=20 chromosomes.

Also:

Bullfrogs with 26 somatic chromosomes (2n) will have 13 chromosomes in the reproductive cells and 26 chromosomes in the zygotes and embryo cells.Mouse with 20 chromosomes in the gamete cells will have 40 chromosomes in the somatic cells and 40 chromosomes in the zygote and embryo cells.Pigeons with 80 chromosomes in the zygotes and embryo cells will have 80 chromosomes in the somatic cells and 40 chromosomes in the gamete cells.Rabbits with 44 somatic chromosomes will have 22 chromosomes in their gamete cells and 44 chromosomes in their zygotes and embryo cells.

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