Which one of the following considerations is relevant to appraisal of the clinical significance of the findings of an experimental study?

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Answer 1

The size of the difference in the treatment groups' outcome means is important in determining the clinical significance of an experimental study's findings.

Critical appraisal is the process of carefully and methodically evaluating the results of scientific research (evidence) to determine its credibility, value, and relevance in a specific context. Critical appraisal examines the methodology of a study and factors such as internal validity, generalizability, and relevance.

Individual clinical expertise is combined with the best available external clinical evidence from systematic research, as well as the patient's values and expectations, in the decision-making process for patient care. It is essential to be able to identify and evaluate the best available evidence in order to integrate it with your clinical experience and the values of your patients. The purpose of this article is to provide a reliable and simple method for determining the credibility of articles and their relevance to clinical practise.

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Related Questions

What would happen if complexes i-iv of the mitochondrial electron transport chain pumped protons in the opposite direction?

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Answer:

If complexes I-IV of the mitochondrial electron transport chain pumped protons in the opposite direction, it would disrupt the process of oxidative phosphorylation, which is the main source of ATP production in the cell. Oxidative phosphorylation occurs when protons are pumped from the matrix of the mitochondria into the intermembrane space by complexes I-IV. This creates a proton gradient across the inner membrane of the mitochondria, which is used by complex V (also known as ATP synthase) to produce ATP.

If the complexes I-IV pumped protons in the opposite direction, the proton gradient across the inner membrane of the mitochondria would be disrupted. This would prevent complex V from functioning properly and producing ATP, resulting in a decrease in ATP production and a reduction in the energy available for the cell to use. This could have negative consequences for the cell, including a decrease in its ability to perform essential cellular functions and maintain homeostasis. (with rizz)

Explanation:

in a food chain, with each feeding relationship, the energy transferred from one organism to another will(1 point)

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Along the food chain, energy is transmitted from one trophic level to the next.

The amount of energy that is actually transmitted to species at the next trophic level is only around 10% of the total energy stored in organisms at one trophic level. The remaining energy is used by metabolism or released into the atmosphere as heat. Energy is never generated nor destroyed and merely transferred or converted from one form to another. In environments where energy is continuously transferred along the food chain, this theory is valid. When one creature feeds another and absorbs the energy-rich molecules from its prey's body, energy is transmitted between trophic levels. The inefficiency of these exchanges, however, limits the length of food chains. Energy is transferred between the species in food webs from producers to consumers. Organisms utilise the energy to complete difficult activities. Solar energy, which accounts for the vast bulk of the energy in food webs, is converted into chemical energy during photosynthesis in plants.

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24. According to the Punnett square above, what percent of offspring will have a tall phenotype?

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Answer:

75 percent

Explanation:

There is only one square with the recessive phenotype tt. This means the rest of the 4 combinations will have the tall phenotype. 4-1 = 3 3/4 = 75 percent.

Answer:

75%

Explanation:

I say 75% because both pea plants have one dominant and one Recessive so by the picture it shows 3/4 having a domminant letter (Big T) and 3/4 in percentage is 75%

please let me know if this is right

which scenarios correctly describe how a specific gametic mutation might alter the sex ratio in the offspring of a childhood cancer survivor?

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The X chromosome scenarios accurately describe how a particular gametic mutation might change the sex ratio in the offspring of a childhood cancer survivor.

A decrease in the frequency of male births can indicate that a recessive lethal gametic mutation has been introduced into the maternal X chromosome.

The two main cell types seen in eukaryotic species are germ and somatic. Both types of cells can experience mutations. A mutation is referred to as a germinal mutation if it occurs in a germ cell. Because gametes develop from germ cells, some gametes will carry the mutation, and when the person successfully mates, they will pass it on to the following generation. Germinal mutations are typically not expressed in the person carrying the mutation. . It would only become apparent if it had a negative (or positive) impact on gamete production. All non-germline tissues are derived from somatic cells. Somatic mutations are changes that occur in somatic cells. The mutations are not sexually transmitted to the following generation because they do not develop in gametes-producing cells.

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m protein, hyaluronidase, collagenase, and often a capsule, can be virulence factors for certain pathogenic strains of

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The streptococcus pathogenic strains are responsible for the protein, hyaluronidase, collagenase, and often a capsule, can be virulence factors.

Streptococci infections are divided into numerous groups: Group A streptococcus, Group B streptococcus, Group C streptococcus, and Group G streptococcus.For some of Gram-advantageous organisms, hyaluronidases had been proven to be crucial virulence elements due to their cappotential to disseminate cells and virulence elements thru tissue.

The M protein coats institution A streptococci (GAS) and acts because the number one antigen and determinant of type-precise immunity. M is crucial for GAS virulence, presenting antiphagocytic capabilities vital to survival in human tissues and fluids.

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anthro which are the most distinctive traits demonstrating the adaptation of neanderthals to cold conditions? group of answer choices their body shape and the length of their arms and legs the retromolar space and heavy wear on their teeth their thick bones with evidence of strong muscles their vertical foreheads and globular shape of the skulls anthro

Answers

The most distinctive trait demonstrating the adaptation of Neanderthals to cold conditions is their body shape and the length of their arms and legs.

Thus, the correct answer is  A.

Neаnderthаls аre а hominin species thаt existed for аt leаst 200,000 yeаrs throughout Europe аnd western Аsiа, аnd disаppeаred аbout 27,000 yeаrs аgo. During this time, they witnessed some of the coldest climаtic conditions ever known in these regions. Mаny of their physicаl feаtures suggest thаt they were аdаpted for the cold, such аs their bаrrel-shаped chests, shorter limbs, аnd lаrger brаins, аll of which suggest а body shаpe аdаpted for retаining heаt.

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With genetic maternal effect, the phenotype of an individual is determined by which of the statements?

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Maternal effect genes have an impact on the embryo's fundamental structure even before the egg has been fertilized.

Explain about the genetic maternal effect?

The phenotypes that correspond to a person's genotype are not always present. In contrast to female progeny, male kids display genotypes similar to their fathers. Progeny exhibit the phenotypes that correspond to their own genes.

Maternal effects are phenotypes that an organism displays, regardless of its own genotype, that are predicted by the mother's genotype. The mother usually gives the egg messenger RNA or proteins, which explains why this happens frequently.

Maternal-effect genes have been discovered by testing whether the mother has a mutant gene that stops her from being able to save her embryo when the father contributes a wild-type gene.

The complete question is,

With genetic maternal effect, the phenotype of an individual is determined by which of the statements ? a. the sex of the individual with only one sex able to express the genotype b. the sex of the parent who transmits the gene to the individual c. a combination of environmental factors and the genotype of the individual d. cytoplasmic genes usually located in the mitochondria e. the nuclear genotype of the maternal parent

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What event occurs only in meiosis ?

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As a result, the correct answer is 'Homologous chromosomal pairing.' Meiosis is the process by which a single cell divides twice to generate four cells with half the original genetic material.

These are our sex cells, sperm in men and eggs in women. Meiosis, on the other hand, is confined to germ cells in multicellular plants and animals,

where it is essential for sexual reproduction. Whereas somatic cells multiply by mitosis, germ cells create haploid gametes through meiosis (the sperm and the egg).

The meiosis is characterised by pairing of homologous chromosomes, exchange of segments between homologous chromosomes and reduction in chromosome number to half.

Whereas somatic cells multiply by mitosis, germ cells create haploid gametes through meiosis (the sperm and the egg).

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A student uses 12 newtons (n) of force to push a box 4 meters (m) down the driveway. How much work did the student do to move the box?.

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The work done by the student to move the box with a force of 12 N at a distance of 4 m is 48 Joule.

Work in physics is the amount of energy given to move an object or object. In simple terms, recognizing effort in physics can be described as someone pushing or pulling an object.

The formula for work (W) = force (F) x displacement/distance (s).

If it is known that the force to push the box is 12N (F) and the displacement is 4 m (s). Then the work done is:

W = F x s

W = 12 x 4

W = 46 Joules

Thus, the work done is 48 J.

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the hypothalamus secretes two types of neurohormones called hormones and hormones.

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The hypothalamus is an important part of the brain that is responsible for controlling and coordinating many of the body's physiological processes. It secretes two types of neurohormones, releasing hormones and inhibiting hormones, which play a key role in regulating hormone production and other bodily functions.

The Role of Neurohormones in Regulating Physiological Processes: The Hypothalamus

1. Releasing hormones: These hormones are secreted from the hypothalamus and travel to the anterior pituitary gland, where they stimulate the release of other hormones. Examples of releasing hormones include:

Growth hormone-releasing hormone (GHRH)Corticotropin-releasing hormone (CRH)Thyrotropin-releasing hormone (TRH)

2. Inhibiting hormones: These hormones are secreted from the hypothalamus and travel to the anterior pituitary gland, where they inhibit the release of other hormones. Examples of inhibiting hormones include:

SomatostatinDopamineProlactin-inhibiting hormone (PIH)

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i need help with this

Answers

Answer: house?

Explanation:

id say the bed or pillow, not the house thatd represent the body

Rats colonize an archipelago in the Pacific Ocean where no rats previously existed. The rats can have white fur, gray fur, or black fur. Predict what type of selection is likely to occur when each of the following phenotypes have the greatest fitness.- grey fur- dark fur- dark fur in fields and light fur in forests- light fur- dark fur on one island, light fur on another

Answers

Directional selection:

- dark fur

- light fur

Stabilizing selection:

- grey fur

Diversifying selection:

- dark fur in fields and light fur in forests

- dark fur on one island, light fur on another

Natural selection is the differential survival and reproduction of individuals as a result of phenotypic differences. The change in the heritable traits characteristic of a population over generations is a key mechanism of evolution. Natural selection was popularized by Charles Darwin, who contrasted it with artificial selection, which, in his opinion, is intentional, whereas natural selection is not.

Variation exists within all organism populations. This occurs in part because random mutations occur in an individual organism's genome, and their offspring can inherit such mutations. Individuals' genomes interact with their environments to cause trait variations throughout their lives. A genome's environment includes molecular biology in the cell, other cells, other individuals, populations, species, and the abiotic environment. The population evolves because individuals with certain variants of the trait tend to survive and reproduce more than individuals with other less successful variants. Sexual selection (now frequently included in natural selection) and fecundity selection are two other factors influencing reproductive success.

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In bacteria, translation of the mrna begins near the 5' end of the mrna molecule, when a(n).

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When an mRNA attaches to the small ribosomal subunit in bacteria, translation of the mRNA starts close to the 5' end of the mRNA molecule.

As soon as mRNA is transcribed in bacteria, it is translated into protein. In contrast to eukaryotic cells, bacteria lack a distinct nucleus that divides DNA from ribosomes, removing a barrier to translation. Transcription and translation take place concurrently in these species. mRNA translation initiation in bacteria begins as soon as the messenger RNA (mRNA) molecule's 5' end has been created. Transcription and translation are interdependent processes that take place in these prokaryotic species. A short ribosomal-binding region that is located near the mRNA's 5' end helps bacterial mRNA bind to the small ribosomal subunit at the beginning stages of translation.

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how does the metabolism occurring in chloroplasts differ from that of mitochondria?

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Metabolism occurring in chloroplasts differ from that of mitochondria, because of different electron acceptors and sources.

Mitochondria and chloroplasts are plant cell organelles. However, chloroplasts are absent in animal cells, whereas mitochondria are found in both.

Mitochondria generate cellular energy in the form of ATP from oxygen and nutrients. Chloroplasts are the place where photosynthesis occurs in plant cells.

Mitochondria are responsible for producing most of the useful energy from the breakdown of lipids and carbohydrates, while chloroplasts use the energy captured from sunlight to produce ATP and convert CO into carbohydrates. Using the reducing power needed to decompose and synthesize CO₂ and H₂O.

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the epithelial lining of the small and large intestines are exposed to a harsh environment and undergo continuous cell loss. in which region do stem cells reside

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In the crypt of the small intestine stem cells reside which helps when the epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss.

The main job of the small intestine is to break down food. However, in addition to creating a number of substances that send signals to various parts of the body, the gut plays a critical role in battling pathogens and preserving the body's water balance. The small intestine's epithelial cells aid in nutrition absorption and digestion. In a similar manner, the epithelial cells secrete a significant quantity of digesting enzymes.

The rough endoplasmic reticulum produces digestive enzymes, which are proteins that are then sorted in the Golgi apparatus and packed into the vesicles. Bicarbonate and other digestive enzymes secreted by the small intestine aid in the breakdown and absorption of nutrients.

The complete question is:

The epithelial lining of the small intestine is exposed to a harsh environment and undergoes continuous cell loss. In which region of the small intestine do stem cells reside?

A. The villus

B. The mesenchyme

C. The goblet

D. The crypt

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which protein is a positive regulator that phosphorylates other proteins when activated?

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Answer:

Cyclin-dependent kinases (Cdks) are protein kinases that, when fully activated, can phosphorylate other proteins.

A marine biologist and cancer researcher worked together to isolate the green fluorescent protein (gfp) gene from a sample of jellyfish dna. scientists have successfully inserted this gene into a cancerous tumor in humans in order for the tumor to glow so it can be more easily removed during surgery. which technology can the scientists use to isolate and extract the gfp gene from the rest of the jellyfish genome for this application? gel electrophoresis polymerase chain reaction artificial selection genetic engineering

Answers

Biotechnology is used by biologists and cancer researchers to isolate green fluorescent protein (GFP) from jellyfish deoxyribonucleic acid (DNA) samples called gel electrophoresis.

Gel electrophoresis is a technique for breaking down a macromolecule by applying a force to the macromolecule to pass through a medium containing a gel assisted by electric power. The working principle of electrophoresis is to separate DNA based on size (molecular weight). This technique is often used in the field of molecular biology to determine the size of a DNA fragment, solve DNA fragments, as well as to test the quality and quantity of samples.

So, to isolate green fluorescent protein (GFP) in jellyfish DNA samples, gel electrophoresis was used.

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reactive oxygen intermediates and reactive nitrogen intermediates produced by phagocytic cells are effective in killing invading microorganisms.a) trueb) false

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True. Reactive oxygen intermediates and reactive nitrogen intermediates produced by phagocytic cells effectively kill invading microorganisms.

The innate immune system is the first line of defense against pathogens and is characterized by a rapid but non-specific response. One of the important mechanisms of this system is the production of reactive oxygen and nitrogen species, which are widely distributed in biological systems, including phagocytes and secretions.

Reactive oxygen and nitrogen species are short-lived media that are biochemically synthesized by various enzymatic reactions in aerobic organisms and regulated by antioxidants. Physiological levels of reactive species play an important role in cell signaling and proliferation.

Reactive Oxygen and Nitrogen Species (RONS) are a group of highly reactive radical and non-radical chemicals that contain oxygen and nitrogen. They appear as by-products or main products of metabolism. At the cellular level, mitochondria produce reactive oxygen species (ROS) as by-products of metabolism.

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????????????????????

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Answer:

what was the question?

the step in photosynthesis and cellular respiration when energy-carrying molecules are formed

Answers

Glycolysis is the step in photosynthesis and cellular respiration when energy-carrying molecules are formed.

What is cellular respiration?

Cellular respiration is the method by which biological fuels are converted into a form that can be oxidized in the presence of an inorganic electron acceptor, such as oxygen, to generate a significant quantity of energy and power the major generation of ATP.

The Krebs cycle, respiratory electron transport, and glycolysis are the three stages of cellular respiration.

What happens during cellular respiration?

Through cellular respiration, organisms mix oxygen with food molecules, directing the chemical energy contained in these substances toward life-sustaining processes while excreting carbon dioxide and water as waste.

Why does cellular respiration occur in plants?

All plant tissues must breathe in order to grow and remain healthy. Additionally, respiration is crucial for the global carbon cycle and the carbon balance of individual cells, entire plants, and ecosystems.

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All organisms are composed of
A. diatoms
B. cellulose
C. cells
D. none of the above

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The answer is c. Cells
C is correct, im from Vietnam

what term is used to describe a period characterized by very high rates of speciation?

Answers

Adaptive radiation is the phrase used to indicate a time when the rate of speciation was extremely high.

A fast growth in the number of species sharing a common ancestor that is marked by high ecological and morphological variety is known as adaptive radiation.

It is fueled by organisms' capacity for ecological adaptation. Adaptive radiation may not necessarily be significant at the scale of the species, but may be significant at a higher taxonomic level, according to Simpson.

Adaptive radiation is the cause of the Galapagos finch variety that was previously explored. It may even be said that their instance is the most well-known and typical adaptive radiation case ever investigated.

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how would you attempt to measure a reaction that is completed within one picosecond? (for example the light-induced electron transfer reaction in the first step of photosynthesis?

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A reaction is said to be "finished" when it reaches equilibrium, or when the concentrations of the reactants and products stop changing. By counting the amount of product produced over a predetermined amount of time, one can determine the reaction's pace.

A solid product's mass is frequently expressed in grams, but a gaseous product's volume is typically expressed in cm3. The duration selected might be influenced by the reaction's rate. Tests that measure reaction times (RTs) are regarded as quick and accurate ways to identify variations in cognitive performance. RT tests track how long passes between a stimulus and a subject's reaction to it.

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the auditory sensory axons of the ____ branch of cranial nerve number ____ terminate in the _____ nucleus within the brainstem.

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Auditory sensory axons of the cochlear branch of cranial nerve number 8 terminates in the cochlear nucleus in the brainstem.

What is cochlear nerve?

The cochlear nerve is also called auditory nerve. It is one of the two parts of the vestibulocochlear nerve: cranial nerve present in amniotes, and the other part is the vestibular nerve. The cochlear nerve carries the auditory sensory information from cochlea of the inner ear to the brain.

Sound stimulus travels to the vestibulocochlear nerve  cranial nerve VIII, and terminates in the cerebral cortex. Cranial nerve VIII is the cranial nerve that is related with hearing, balance, and head position.

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Forces work in pairs; the _____ force is the initial force applied to an object.

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The net force is the initial force applied to an object.

What about net force?The total of all forces exerted on an object is known as the net force.  When there are a lot of forces acting on a system, the term "net force" is employed.The net force is the total of all forces acting on an object. According to Newton's Second Law, there must be a net force exerted on an item in order for it to accelerate. If an object's net force is zero, it is said to be in equilibrium and not moving forward.The total amount of forces exerted on an object is referred to as its net force. The total of N forces exerted on an item is given in the equation below. The total force operating on an item, which may include a number of different forces, is known as the net force acting on the object.Net force is significant since it aids in describing the object's motion and can be used to calculate acceleration. According to Newton's first law of motion, unless acted upon by an imbalanced net force.An object at rest will remain at rest, while an object in motion will continue to be in motion.

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write a comment for this do you agree or disagree and tell me why I think heart disease is so prevalent in the United States because theres a lot of smoking that everyone does out here.Heart disease is the leading cause of death among both men and women in the United States.Also if people will stop smoking or keep there body healthy in United States a lot of people wouldn't be having to worry about heart disease.Heart disease is very important because a lot of things can cause it and people should stop smoking in United States.

Answers

Heart disease could be prevalent in the United States  but not because people do smoke alot, because there are other factors that can as well result to heart disease apart from smoking.

What are the Cuases of Heart disease?

A buildup of fatty plaques in the arteries can be described as one of the   common cause of coronary artery disease and this can be regarded as the atherosclerosis, however some of the risk factors  that can be attributed to this is the poor diet, lack of exercise as well as obesity and smoking.

It should be noted that the Healthy lifestyle choices can  contribute to the decrease in the risk of atherosclerosis however leading risk factors for heart disease  can as well be attributed to the high blood pressure as well as the high low-density lipoprotein  but one of the common of this is the , smoking  as well as  unhealthy diet, and physical inactivity.

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Can humans ever directly see a photon?

Answers

Answer:

Yes. In fact, photons are the only things that humans can directly see. A photon is a bit of light. Human eyes are specifically designed to detect light.

how long does it take for humoral immunity to accomplish antibody production in the first exposure to the pathogen?

Answers

It takes 3-6 days for humoral immunity to accomplish antibody production in the first exposure to the pathogen.

The question discusses about immune kinetics of the body. The immune kinetics is associated with onset of development and action of antibodies form the infection in the body.

The igM ang igG are produced on infection or pathogen. igM is produced early while igG is produced late. However, former is short lived and latter has long life. Moreover, igM is the very first antibody produced indicating recent infection.

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What’s the function of cartilage in the gas exchange system?

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Answer:

Cartilage plays a crucial role in the gas exchange system by supporting and protecting the delicate structures of the respiratory system. In particular, cartilage helps to maintain the shape of the trachea (windpipe) and bronchi (airways), which allows air to flow freely through the respiratory system.

Cartilage is a tough, flexible tissue that is composed of cells called chondrocytes, as well as a strong, fibrous extracellular matrix. The cartilage in the respiratory system is mostly made up of elastic cartilage, which is highly resilient and can withstand the forces of breathing.

The cartilage in the respiratory system also helps to prevent the airways from collapsing or becoming blocked, which would impede the flow of air. For example, the cartilage rings that surround the trachea provide structural support and keep the trachea open, allowing air to pass through easily.

In summary, the function of cartilage in the gas exchange system is to support and protect the structures of the respiratory system, allowing air to flow freely through the airways and facilitating gas exchange in the lungs.

how are the vascular plants that are involved in mycorrhizal associations and the photosynthetic cells involved in lichens alike

Answers

They give their fungi partners organic nutrients.

Fantastic nutrient recyclers are fungi. The number of fungus species is around 140,000. Millions more may yet be found, according to speculation. How do fungi acquire their nutrients given that there are so many different varieties of fungi

In addition to being wonderful on pizza or in an omelet, fungi are also useful for baking, making wine, manufacturing cheese, and creating antibiotics.

Foods (like fruits) and other substances/items can support the growth of fungi. Both plants and people can contract diseases from fungi, which can also be parasitic.

Symbiotic interactions between fungi and plants are known as mycorrhizae. A host plant's root system is colonized by fungi, which increase the plant's ability to absorb water and nutrients while giving the fungus access to the plant's carbohydrates produced during photosynthesis.

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